Primary cells have been the center of in vitro research. With their tissue-specific characteristics, they have offered insights that augmented our level of understanding of the cell biology, genetic profile, physiological processes, signaling pathways, and disease pathophysiology. It has significantly accelerated drug discovery, development by serving as a s...
Human Bone Marrow Derived Hematopoietic Stem Cells- the first stem cells to be identified and approved for therapy. These CD34-positive stem cells can develop the entire blood cell lineage and the entire immune system. These cells have been applicable in malignant and non-malignant disorders related to blood and immune cells. They are widely applied in resea...
Primary cells - discover the hidden secrets behind tissue functioning. These cells offer valuable insights by serving as a suitable model for in vitro studies. The most commonly employed among them belong to humans and mice. Human primary cells are effective for modeling human disease and outlining underlying pathways. Although they have more physiological r...
Primary bone cells- the primary mediators of bone development and dysfunction. Bone cells, namely osteoblasts and osteoclasts, are essential for bone formation. Their coordinated efforts shape the skeletal system and maintain homeostasis. Any dysregulation can result in injury, osteoporosis, arthritis, cancer, etc. Therefore, research into their cellular sig...
Swine kidney fibroblasts-the structural support of the tissue. Located in the interstitial space between nephrons and blood vessels, these cells exhibit an elongated, spindle-shaped morphology with dense endoplasmic reticulum and granules filled with extracellular matrix proteins. Through their cytoplasmic extensions, they connect to different renal cells an...
