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Primary cells have tissue characteristics, whereas cell lines are easier to culture. The debate of primary cells versus cell lines has been going on for a long time. It all boils down to the research study and its applications. For in vivo reproducibility, primary cells are the best bet, whereas cell lines are suitable for cancer research, bioproduct manufac...
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Primary cells have been the center of in vitro research. With their tissue-specific characteristics, they have offered insights that augmented our level of understanding of the cell biology, genetic profile, physiological processes, signaling pathways, and disease pathophysiology. It has significantly accelerated drug discovery, development by serving as a s...
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Primary cells - discover the hidden secrets behind tissue functioning. These cells offer valuable insights by serving as a suitable model for in vitro studies. The most commonly employed among them belong to humans and mice. Human primary cells are effective for modeling human disease and outlining underlying pathways. Although they have more physiological r...
Swine kidney fibroblasts-the structural support of the tissue. Located in the interstitial space between nephrons and blood vessels, these cells exhibit an elongated, spindle-shaped morphology with dense endoplasmic reticulum and granules filled with extracellular matrix proteins. Through their cytoplasmic extensions, they connect to different renal cells an...
